Answer
May 20, 2025 - 07:09 AM
Ibuprofen has a black box warning due to its potential to increase the risk of serious cardiovascular events, such as heart attack and stroke, especially with long-term use or in people with existing heart conditions. Additionally, it can cause gastrointestinal issues, including bleeding, ulceration, and perforation of the stomach or intestines, which can be serious or even fatal. These risks necessitate caution and close monitoring when using the medication.
